Research Associate Support Resource – Molecular Biology & Cell-based Assay (Analytical Development)

SGS_JOB_3278

Business Support
 California
PCR
qPCR
ddPCR
ELISA
Gel Electrophoresis
Mammalian Cell Culture
Cell-based Assays
Molecular Biology Techniques
Analytical Method Development
Assay Transfer
Data Analysis
ELN Documentation

Contract - 12 months + (possible extension)

Location (mandatory): South San Francisco, CA, USA, 94080 (On-site) The contractor Research Associate will support the Analytical Development team within the Tech Dev department by developing, optimizing, and executing molecular biology and cell-based assays. The role involves hands-on laboratory work, data analysis, documentation, and cross-functional collaboration in a hypothesis-driven R&D environment at the South San Francisco facility.

Job Responsibilities:

  •  Develop, optimize, and execute analytical assays for proteins, DNA, adeno-associated viral (AAV) nanoparticles, and related cell-based assays.
  •  Perform routine testing using established SOPs and applicable regulatory guidelines, including ddPCR/qPCR, ELISA, and mammalian cell-based assays.
  •  Support assay transfer to internal partners (QC, testing, and research teams), including documentation, troubleshooting, and method comparability.
  •  Analyze experimental data, assess data quality, determine applicability to project goals, draw conclusions, and make data-driven recommendations.
  •  Author, review, and revise experimental procedures, protocols, and technical reports.
  •  Maintain accurate, timely, and compliant records of analytical development activities in laboratory notebooks, ELN, and data systems.
  •  Summarize and present experimental results in meetings and participate in report writing.
  •  Contribute to a collaborative laboratory environment by sharing technical insights, supporting cross-functional projects, and improving workflows.

Skills:

  •  Proficiency in mammalian cell-based assays and PCR-based assays (qPCR, ddPCR).
  •  Hands-on experience performing quantitative assays such as ELISA for characterization of proteins, nucleic acids, viruses, or other biological products.
  •  Strong experience with sterile technique and mammalian cell culture, including cell maintenance, expansion, characterization, and banking.
  •  Working knowledge of molecular biology techniques including DNA/RNA/protein isolation, cDNA synthesis, RT-PCR, qPCR, and digital PCR.
  •  Ability to independently plan, execute, troubleshoot, and document experiments in a fast-paced, collaborative environment.
  •  Strong analytical thinking, attention to detail, and commitment to generating high-quality, reproducible data.
  •  Excellent written and verbal communication skills for presenting technical data to technical and non-technical audiences.
  •  Proficiency with Microsoft Office and standard data analysis and documentation tools.

Education/Experience:

  •  Experience working with Adeno-Associated Virus (AAV).
  •  Experience in analytical method development and assay transfer.
  •  Experience in basic statistical analysis.
  •  B.S. in Biology, Biochemistry, Molecular Biology, or a related discipline.
  •  1+ years of industry experience in pharmaceutical or biotechnology environments.

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