Research Associate

SGS_JOB_3625

Business Support
 California
Biophysical
Electrophoresis
SDS-PAGE
DLS
MALS
AUC

Contract - 06 months Contract

Location : South San Francisco CA USA 94080 The primary responsibilities of the Biophysical Assay Research Associate will include performing analytical method development and testing samples using Capillary Electrophoresis, SDS-PAGE, DLS, MALS, AUC, and other analytical tools; contributing to design and performing experiments with supervision as needed; completing assigned tasks within time frames with high quality; maintaining a well-documented record of activities in lab notebook and reports. The position level will commensurate with education and experience level. Additionally, the role includes regularly summarizing and presenting experimental results in lab meetings and responsible for generating reports. This role will be at our South San Francisco location.

Job Responsibilities:

  •  Conducting experiments to characterize adeno-associated viral nanoparticles for gene therapy products.
  •  Performing assays for particle/protein/DNA in multiple assays (Capillary Electrophoresis, SDS-PAGE, DLS, Western Blot, Light Obscuration, AUC, RP, SE – HPLC methods, etc.) to assist in evaluation of product characterization, including but not limited to: process change, formulation study, stability study using statistical methods as needed, following SOPs and execute experiments according to guidelines.
  •  Developing new assays and transfer to QC, Process Development, and Research.
  •  Developing new analytical tools to characterize adeno associated viral nanoparticles for gene therapy products
  •  Participating in writing, reviewing, and editing experimental procedures and reports
  •  Maintaining accurate records of all analytical development activities timely
  •  Analyzing and determining the applicability of laboratory data to draw conclusions and to make appropriate recommendations

Skills:

  • Direct, hands-on experience with adeno-associated viral nanoparticles.
  • Experience operating chromatography methods (HPLC, etc.) and proficient understanding of chromatography software.
  • Experience operating general ultracentrifugation methods.
  • Experience operating PCR methods.
  • Experience in analytical method development and assay transfer.
  • Experience in statistical analysis with proficiency in statistical analysis software.

Education/Experience:

  • Bachelor of Science with 2+ years of experience working in a pharmaceutical or biotech company and with the requisite years’ of experience employing the skills listed in the job description (for each level) performing multiple assays for bioproducts.

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